SCHEMBL1401930

SCHEMBL1401930

C1CCOCOCCCCOCOC1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
TSHR P16473 2/20 0.46
TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27370 1.00
SCHEMBL2125743 0.95
SCHEMBL11788532 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
SCHEMBL8387818 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
SCHEMBL4788084 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
SCHEMBL8384141 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
SCHEMBL1080336 0.95
SCHEMBL8387990 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
SCHEMBL9147127 0.95 ALDH1A1 (0.58) ALDH1A1TSHRTTR
Tetrahydrofuran SCHEMBL23573614 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153259-A1 HIP LABRUM SCAFFOLDS Orteq B.V. (NL) 2023-03-29 EP claimed
WO-2021236151-A1 HIP LABRUM SCAFFOLDS ORTEQ B.V. (NL) 2021-11-25 WO claimed
EP-4153259-A1 HIP LABRUM SCAFFOLDS Orteq B.V. (NL) 2023-03-29 EP disclosed
WO-2021236151-A1 HIP LABRUM SCAFFOLDS ORTEQ B.V. (NL) 2021-11-25 WO disclosed
US-20210361832-A1 HIP LABRUM SCAFFOLDS ORTEQ B.V. (NL) 2021-11-25 US disclosed
WO-2015134028-A1 POLYURETHANE FOAM FOR USE IN MEDICAL IMPLANTS ORTEQ INC (US) 2015-09-11 WO disclosed
EP-2570440-A2 Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds Orteq B.V. (NL) 2013-03-20 EP disclosed
EP-1594908-B1 METHOD FOR THE PREPARATION OF NEW SEGMENTED POLYURETHANES WITH HIGH TEAR AND TENSILE STRENGTHS AND METHOD FOR MAKING POROUS SCAFFOLDS ORTEQ B V (NL) 2012-08-01 EP disclosed
US-7943678-B2 Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds Orteq, B.V. (NL) 2011-05-17 US disclosed
US-20110105635-A1 POLYURETHANE FOAM FOR USE IN MEDICAL IMPLANTS ORTEQ B.V. (NL) 2011-05-05 US disclosed
EP-2291206-A2 POLYURETHANE FOAM FOR USE IN MEDICAL IMPLANTS Orteq B.V. (NL) 2011-03-09 EP disclosed
WO-2009141732-A2 POLYURETHANE FOAM FOR USE IN MEDICAL IMPLANTS ORTEQ B.V. (NL) 2009-11-26 WO disclosed
US-20070037954-A1 Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds HEIJKANTS RALF GUILLAUME J C 2007-02-15 US disclosed
US-20070015894-A1 Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds ORTEQ B.V. (NL) 2007-01-18 US disclosed
EP-1594908-A1 METHOD FOR THE PREPARATION OF NEW SEGMENTED POLYURETHANES WITH HIGH TEAR AND TENSILE STRENGTHS AND METHOD FOR MAKING POROUS SCAFFOLDS Orteq B.V. (NL) 2005-11-16 EP disclosed
WO-2004074342-A1 METHOD FOR THE PREPARATION OF NEW SEGMENTED POLYURETHANES WITH HIGH TEAR AND TENSILE STRENGTHS AND METHOD FOR MAKING POROUS SCAFFOLDS ORTEQ B.V. (NL) 2004-09-02 WO disclosed