SCHEMBL9147127

SCHEMBL9147127

C1CCOCOC1.C1COCO1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
TSHR P16473 2/20 0.42
TTR P02766 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL23573614 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTTR
SCHEMBL7758217 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTTR
SCHEMBL9539378 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTTR
Tetrahydrofuran SCHEMBL2360611 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTTR
Dioxane SCHEMBL5598923 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTTR
SCHEMBL1401930 0.95 ALDH1A1 (0.64) ALDH1A1TSHRTTR
SCHEMBL27370 0.95
SCHEMBL1890967 0.92 ALDH1A1 (0.61) ALDH1A1TSHRTTR
SCHEMBL8720707 0.92 ALDH1A1 (0.61) ALDH1A1TSHRTTR
SCHEMBL8387990 0.91 ALDH1A1 (0.58) ALDH1A1TSHRTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5412042-A Amorphous, blends with crystalline acetal resins have improved impact strength HOECHST CELANESE CORP. (US) 1995-05-02 US claimed
US-5166224-A Polymerization of 1,3-dioxolane, 1,3-dioxepane and cyclic formal, blending and curing HOECHST CELANESE CORP. (US) 1992-11-24 US disclosed