Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.35 |
| ▸ | CPB1 | P15086 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693106 | 0.84 | CYP2C9 (0.44) | CPB2CPB1ALDH1A1 | |
| SCHEMBL2736340 | 0.84 | CYP2C9 (0.44) | CPB2CPB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29400350 | 0.82 | TDP1 (0.45) | CPB2CPB1ALDH1A1 | |
| SCHEMBL7950368 | 0.82 | CPB2 (0.35) | CPB2CPB1ALDH1A1SIRT2PTGS2 | |
| SCHEMBL15307666 | 0.82 | SIRT2 (0.40) | CPB2CPB1ALDH1A1SIRT2 | |
| Hydrochloric Acid SCHEMBL2939066 | 0.81 | ALDH1A1 (0.36) | CPB2CPB1ALDH1A1SIRT2PTGS2 | |
| SCHEMBL8348975 | 0.79 | CPB2 (0.57) | CPB2CPB1 | |
| SCHEMBL13617438 | 0.77 | CPB2 (0.59) | CPB2CPB1SIRT2 | |
| SCHEMBL30786466 | 0.77 | CPB2 (0.37) | CPB2CPB1SIRT2 | |
| SCHEMBL8349095 | 0.77 | CPB2 (0.44) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255090-A1 | Ceratamines A and B, and Analogues, Syntheses and Pharmaceutical Compositions Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-10-16 | — | — | US | disclosed |
| US-20080255090-A1 | Ceratamines A and B, and Analogues, Syntheses and Pharmaceutical Compositions Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255090-A1 | Ceratamines A and B, and Analogues, Syntheses and Pharmaceutical Compositions Thereof | MSR1, HRH3, SNRPD3 | CPB2 3941/4885CPB1 3889/4885ALDH1A1 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.