SCHEMBL14020148

SCHEMBL14020148

C=C1C=CC(=O)N1CN1C(=C)C=CC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.46
FAAH O00519 4/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
BLM P54132 2/20 0.46
GMNN O75496 1/20 0.46
THPO P40225 1/20 0.46
PMP22 Q01453 1/20 0.46
HPGD P15428 2/20 0.44
HSP90AA1 P07900 1/20 0.44
TLR9 Q9NR96 1/20 0.44
TP53 P04637 1/20 0.44
PKM P14618 1/20 0.44
XBP1 P17861 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17190596 0.82 MGLL (0.56) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL7932623 0.80
SCHEMBL114195 0.80 MGLL (0.58) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL23153500 0.78 MGLL (0.65) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL17931554 0.78 MGLL (0.73) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL12056284 0.77 MGLL (0.50) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL24687311 0.77 MGLL (0.44) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14286721 0.75 MGLL (0.75) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL13213415 0.73 MGLL (0.46) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL17300569 0.73 MGLL (0.52) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442734-B2 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2008-10-28 US disclosed