⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056284 | 0.82 | MGLL (0.50) | — | |
| N-Ethylmaleimide SCHEMBL19666 | 0.82 | — | — | |
| N-Ethylmaleimide SCHEMBL18209592 | 0.82 | MGLL (1.00) | — | |
| SCHEMBL14020148 | 0.80 | MGLL (0.46) | — | |
| N-Ethylmaleimide SCHEMBL28905027 | 0.79 | MGLL (0.94) | — | |
| SCHEMBL17563458 | 0.79 | MGLL (0.62) | — | |
| SCHEMBL17190596 | 0.78 | MGLL (0.56) | — | |
| SCHEMBL14868092 | 0.77 | MGLL (0.44) | — | |
| N-Ethylmaleimide SCHEMBL3675197 | 0.77 | MGLL (0.89) | — | |
| N-Ethylmaleimide SCHEMBL4636622 | 0.76 | MGLL (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326292-A1 | POLYMERS OF MALEIMIDE AND CYCLOOLEFINIC MONOMERS AS PERMANENT DIELECTRIC MATERIALS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-11-10 | — | — | US | disclosed |
| WO-2010033216-A1 | POLYMER CONJUGATES OF NESIRITIDE PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033218-A1 | POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033222-A2 | POLYMER CONJUGATES OF ZICONOTIDE PEPTIDES | NETKAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033239-A1 | POLYMER CONJUGATES OF BIPHALIN PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033207-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033217-A1 | POLYMER CONJUGATES OF CD-NP PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |