SCHEMBL13420796

SCHEMBL13420796

O=S(=O)(O)OOC#CSc1ccc(N=Nc2c(SOOO)cc3cc(S(=O)(=O)O)cc(Nc4nc(Cl)nc(Cl)n4)c3c2O)cc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.43
▸ ENPP2 Q13822 1/20 0.32
▸ CARM1 Q86X55 1/20 0.32
▸ PRMT1 Q99873 1/20 0.32
▸ PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084627 0.88 FUT8 (0.42) FUT8
SCHEMBL14020359 0.87 FUT8 (0.42) FUT8
SCHEMBL14084622 0.85 FUT8 (0.44) FUT8
SCHEMBL14084616 0.85 FUT8 (0.42) FUT8
SCHEMBL14020352 0.85 FUT8 (0.41) FUT8
SCHEMBL14020350 0.84 FUT8 (0.43) FUT8
SCHEMBL14084621 0.83 FUT8 (0.32) FUT8CARM1PRMT1PTPN11
SCHEMBL14020355 0.82 FUT8 (0.32) FUT8CARM1PRMT1PTPN11
SCHEMBL14084614 0.79 PRMT1 (0.41) ENPP2CARM1PRMT1
SCHEMBL14084620 0.79 FUT8 (0.39) FUT8ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683208-B2 Bridge compound with N,N-dialkylamino group and application thereof EVERLIGHT USA, INC. (US) 2010-03-23 — — US disclosed
US-20090054645-A1 Bridge compound with N, N-dialkylamino group and application thereof EVERLIGHT USA, INC. (US) 2009-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054645-A1 Bridge compound with N, N-dialkylamino group and application thereof ALKBH1, ALKBH2, B2M FUT8 886/4885ENPP2 4800/4885CARM1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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