SCHEMBL14020372

SCHEMBL14020372

C=C(OO)Sc1nc(Cl)nc(Nc2ccc(S(=O)(=O)O)c(N=Nc3c(SOOO)cc4cc(Nc5nc(Cl)nc(SCC(=O)O)n5)ccc4c3O)c2)n1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.37
▸ CARM1 Q86X55 1/20 0.37
▸ FUT8 Q9BYC5 1/20 0.36
▸ ENPP2 Q13822 4/20 0.32
▸ PRMT3 O60678 1/20 0.31
▸ EP300 Q09472 1/20 0.31
▸ PRMT6 Q96LA8 1/20 0.31
▸ CD40 P25942 1/20 0.31
▸ CD40LG P29965 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084634 0.88 FUT8 (0.38) FUT8ENPP2
SCHEMBL14020369 0.83 FUT8 (0.38) FUT8ENPP2
SCHEMBL14020368 0.82 FUT8 (0.42) PRMT1CARM1FUT8ENPP2
SCHEMBL14020373 0.81 FUT8 (0.52) PRMT1CARM1FUT8ENPP2
SCHEMBL14270442 0.80 FUT8 (0.39) PRMT1CARM1FUT8ENPP2
SCHEMBL14084647 0.79 FUT8 (0.40) PRMT1CARM1FUT8ENPP2
SCHEMBL14020344 0.78 PRMT1 (0.43) PRMT1CARM1FUT8ENPP2PRMT3
SCHEMBL14045203 0.78 PRMT1 (0.42) PRMT1CARM1FUT8ENPP2PRMT3
SCHEMBL14084613 0.77 PRMT1 (0.43) PRMT1CARM1FUT8ENPP2PRMT3
SCHEMBL14020342 0.77 PRMT1 (0.40) PRMT1CARM1ENPP2PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 — — US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 PRMT1 496/4885CARM1 365/4885FUT8 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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