SCHEMBL14020373

SCHEMBL14020373

C=C(OO)Sc1nc(Cl)nc(Nc2ccc(S(=O)(=O)O)c(N=Nc3c(SOOO)cc4cc(S(=O)(=O)O)cc(Nc5nc(Cl)nc(SC)n5)c4c3O)c2)n1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.52
▸ PRMT1 Q99873 2/20 0.32
▸ CARM1 Q86X55 1/20 0.32
▸ ENPP2 Q13822 2/20 0.31
▸ USP2 O75604 1/20 0.30
▸ APEX1 P27695 1/20 0.30
▸ CHAT P28329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084647 0.83 FUT8 (0.40) FUT8PRMT1CARM1ENPP2
SCHEMBL12136693 0.81 FUT8 (0.63) FUT8PRMT1CARM1ENPP2USP2
SCHEMBL14020372 0.81 PRMT1 (0.37) FUT8PRMT1CARM1ENPP2
SCHEMBL14500860 0.80 FUT8 (0.74) FUT8PRMT1ENPP2USP2APEX1
SCHEMBL14084634 0.79 FUT8 (0.38) FUT8ENPP2
SCHEMBL14045198 0.78 FUT8 (0.58) FUT8PRMT1CARM1ENPP2USP2
SCHEMBL14020346 0.77 FUT8 (0.42) FUT8PRMT1ENPP2
SCHEMBL12589891 0.77 FUT8 (0.65) FUT8PRMT1ENPP2USP2APEX1
SCHEMBL14020348 0.77 FUT8 (0.43) FUT8PRMT1CARM1ENPP2
SCHEMBL13599566 0.77 FUT8 (0.51) FUT8PRMT1CARM1ENPP2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 — — US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 FUT8 672/4885PRMT1 496/4885CARM1 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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