Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.52 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774529 | 0.88 | TP53 (0.54) | CETPKMT2ATHRBMEN1ASAH2 | |
| SCHEMBL574816 | 0.84 | KMT2A (0.64) | KMT2ATLR2 | |
| SCHEMBL7132449 | 0.78 | KMT2A (0.75) | KMT2AASAH1TLR2 | |
| SCHEMBL26512839 | 0.78 | TLR2 (0.61) | KMT2ATLR2 | |
| SCHEMBL4572008 | 0.77 | KMT2A (0.73) | KMT2AMEN1TLR2 | |
| SCHEMBL13587937 | 0.77 | KMT2A (0.45) | KMT2ATLR2 | |
| SCHEMBL17701303 | 0.77 | CETP (0.82) | CETPKMT2ATHRBMEN1ASAH2 | |
| SCHEMBL17701304 | 0.77 | CETP (0.82) | CETPKMT2ATHRBMEN1ASAH2 | |
| SCHEMBL8236471 | 0.76 | KMT2A (0.70) | KMT2A | |
| SCHEMBL24032894 | 0.76 | CETP (1.00) | CETPKMT2ATHRBMEN1ASAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262254-A1 | Sphingolipids | ETTMAYER PETER | 2008-10-23 | — | — | US | disclosed |
| US-20080262254-A1 | Sphingolipids | ETTMAYER PETER | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262254-A1 | Sphingolipids | SGMS2, SGMS1, SGPL1 | CETP 239/4885KMT2A 2656/4885THRB 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.