Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.71 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.70 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133213 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL13863420 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22973496 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL5527047 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22911186 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22973426 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22973497 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22910831 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL22910800 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 | |
| SCHEMBL14032326 | 1.00 | CETP (1.00) | CETPTHRBMEN1KMT2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20220016029-A1 | MULTI-PEG LIPID COMPOUNDS | TRANSLATE BIO, INC. | 2022-01-20 | — | — | US | disclosed |
| WO-2021231697-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016029-A1 | MULTI-PEG LIPID COMPOUNDS | LIPG, HDLBP, LIPC | CETP 4/4885THRB 2625/4885MEN1 3889/4885 |
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | LIPG, ABCB4, HDLBP | CETP 14/4885THRB 1980/4885MEN1 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.