Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 8/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021848 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11BCHEFFAR1MAOB | |
| SCHEMBL10548729 | 0.84 | CYSLTR1 (0.56) | — | |
| SCHEMBL3886612 | 0.83 | BCHE (0.49) | CYP4F2CYP4A11BCHEMAOBALDH1A1 | |
| SCHEMBL1745631 | 0.79 | FFAR1 (0.57) | FFAR1MAOB | |
| SCHEMBL8192007 | 0.78 | CYP4F2 (0.68) | CYP4F2CYP4A11BCHEFFAR1MAOB | |
| SCHEMBL14021516 | 0.78 | LTA4H (0.46) | BCHEMAOBLMNASMN1; SMN2MAOA | |
| SCHEMBL14021496 | 0.77 | CYSLTR2 (0.47) | — | |
| SCHEMBL10925207 | 0.77 | HCAR2 (0.36) | MAOBSMN1; SMN2MAOA | |
| SCHEMBL9818406 | 0.77 | CYSLTR1 (0.55) | — | |
| SCHEMBL3884175 | 0.76 | MAOB (0.44) | CYP4F2CYP4A11BCHEMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |