SCHEMBL1402160

SCHEMBL1402160

CCOc1cc(CCNC(=O)C(NS(C)(=O)=O)C(C)C)ccc1OCC#Cc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.44
KMT2A Q03164 6/20 0.42
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.41
GAA P10253 1/20 0.41
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483297 0.93 KMT2A (0.48) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL29419083 0.93 KMT2A (0.48) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL157178 0.93 KMT2A (0.48) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL82268 0.93 KMT2A (0.48) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL1612770 0.90 KMT2A (0.49) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL2436455 0.87 KMT2A (0.46) LMNASMN1; SMN2KMT2AMEN1GAA
SCHEMBL157766 0.87 KMT2A (0.47) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL29408450 0.87 KMT2A (0.47) LMNASMN1; SMN2KMT2APOLBMEN1
SCHEMBL6711496 0.86 KMT2A (0.50) LMNAKMT2APOLBMEN1
SCHEMBL7026780 0.85 KMT2A (0.41) LMNASMN1; SMN2KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP disclosed
EP-3510869-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2019-07-17 EP disclosed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP disclosed
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2017-11-09 US disclosed
US-9743674-B2 Combinations comprising a fungicidal strain and an active compound BAYER CROPSCIENCE LP (US) 2017-08-29 US disclosed
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2016-10-13 US disclosed
US-9392797-B2 Combinations comprising a fungicidal strain and an active compound BAYER CROPSCIENCE LP (US) 2016-07-19 US disclosed
US-20150264939-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2015-09-24 US disclosed
US-9078447-B2 Combinations comprising a fungicidal strain and an active compound BAYER CROPSCIENCE LP (US) 2015-07-14 US disclosed
EP-2614717-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2013-07-17 EP disclosed
EP-2319320-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-11 EP disclosed
EP-2292098-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP disclosed
EP-2292099-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP disclosed
US-20100209410-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BASF SE (DE) 2010-08-19 US disclosed
EP-2192841-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AT LEAST ONE ADDITIONAL FUNGICIDE Basf Se (DE) 2010-06-09 EP disclosed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 US disclosed
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2010-02-11 US disclosed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP disclosed
WO-2009037242-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BASF SE (DE) 2009-03-26 WO disclosed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209410-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL LMNA 1305/4885SMN1; SMN2 742/4885KMT2A 3019/4885
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL LMNA 1497/4885SMN1; SMN2 841/4885KMT2A 3429/4885
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL LMNA 1317/4885SMN1; SMN2 819/4885KMT2A 3555/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 LMNA 4263/4885SMN1; SMN2 4381/4885KMT2A 2543/4885
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides CBR3, CBR1, HCN2 LMNA 2198/4885SMN1; SMN2 3901/4885KMT2A 1943/4885
US-20150264939-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL LMNA 1317/4885SMN1; SMN2 819/4885KMT2A 3555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.