SCHEMBL157178

SCHEMBL157178

COc1cc(CCNC(=O)C(NS(C)(=O)=O)C(C)C)ccc1OCC#Cc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
GAA P10253 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
CNR1 P21554 1/20 0.45
CTSD P07339 2/20 0.43
POLB P06746 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGER1 P34995 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419083 1.00 KMT2A (0.48) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL82268 1.00 KMT2A (0.48) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL483297 1.00 KMT2A (0.48) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL1612770 0.97 KMT2A (0.49) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL2436455 0.93 KMT2A (0.46) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL1402160 0.93 LMNA (0.48) KMT2AMEN1GAALMNASMN1; SMN2
SCHEMBL157766 0.93 KMT2A (0.47) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL29408450 0.93 KMT2A (0.47) KMT2AMEN1GAAALDH1A1LMNA
SCHEMBL7689446 0.92 SMN1; SMN2 (0.46) KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL7099648 0.92 MEN1 (0.49) KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646109-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS Invaio Sciences, Inc. (US) 2025-11-12 EP claimed
US-20250089717-A1 FUNGICIDAL HALOMETHYL KETONES, HYDRATES AND ENOL ETHERS AND THEIR MIXTURES FMC CORP (US) 2025-03-20 US claimed
US-12163142-B2 Methods for manufacturing plant messenger packs FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-12-10 US claimed
WO-2024168193-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS INVAIO SCIENCES, INC. (US) 2024-08-15 WO claimed
US-20240141370-A1 AGRICULTURAL COMPOSITIONS AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2024-05-02 US claimed
EP-4361150-A2 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC Corporation (US) 2024-05-01 EP claimed
US-20240122180-A1 FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES FMC CORPORATION 2024-04-18 US claimed
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION 2024-03-21 US claimed
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
EP-4262396-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2023-10-25 EP claimed
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens BASF AKTIENGESELLSCHAFT (DE) 2008-02-21 US claimed
WO-2007104669-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2007-09-20 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
EP-1813152-A1 Fungicidal mixture based on 3,4-disubstituted biphenylanilides BASF AKTIENGESELLSCHAFT (DE) 2007-08-01 EP claimed
EP-1813151-A1 Fungicidal compositions based on 1-methyl-pyrazol-4-yl-anilides BASF Aktiengesellschaft (DE) 2007-08-01 EP claimed
WO-2007010036-A2 FUNGICIDALLY ACTIVE AGENT BASF AKTIENGESELLSCHAFT (DE) 2007-01-25 WO claimed
WO-2007003603-A2 FUNGICIDE MIXTURES BASED ON 3-MONOSUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYL AMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO claimed
WO-2007003540-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO claimed
WO-2007003643-A1 FUNGICIDAL MIXTURES BASED ON 3,4-DISUBSTITUTED PYRAZOLECARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO claimed
WO-2007000462-A1 FUNGICIDE MIXTURES BASED ON 2,4-DISUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES NOX1, TH, NOX3 KMT2A 3921/4885MEN1 2484/4885GAA 1680/4885
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens DDT, CYP4X1, STS KMT2A 2907/4885MEN1 420/4885GAA 2017/4885
US-20240122180-A1 FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES AKR7A2, TBCA, TUBA1C KMT2A 909/4885MEN1 3080/4885GAA 636/4885
US-20250089717-A1 FUNGICIDAL HALOMETHYL KETONES, HYDRATES AND ENOL ETHERS AND THEIR MIXTURES HCN2, CYP8B1, TUBA3C KMT2A 1241/4885MEN1 3315/4885GAA 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.