Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11776063 | 0.98 | MAPT (0.64) | MAPTGAAPLA2G4BSMN1; SMN2POLB | |
| SCHEMBL177201 | 0.88 | PLA2G4B (0.65) | MAPTPLA2G4BTSHRCASP6HCAR3 | |
| SCHEMBL2339687 | 0.88 | POLB (0.73) | MAPTGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3537490 | 0.88 | MAPT (0.62) | MAPTGAAPOLBTSHRCASP6 | |
| SCHEMBL27403163 | 0.87 | PLA2G4B (0.74) | MAPTPLA2G4BALDH1A1HCAR3LMNA | |
| SCHEMBL1749792 | 0.87 | PLA2G4B (0.74) | MAPTPLA2G4BALDH1A1HCAR3PRSS1 | |
| Hydrochloric Acid SCHEMBL3729179 | 0.87 | MAPT (0.60) | MAPTGAAPOLBTSHRCASP6 | |
| SCHEMBL29682151 | 0.87 | GAA (0.62) | MAPTGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11691516 | 0.87 | GAA (0.62) | MAPTGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6113984 | 0.87 | GAA (0.62) | MAPTGAASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183348-B | N- (3-nitro-4-alkoxy benzoyl) amino acid compound, preparation method and application thereof | 中国医科大学 | 2022-06-03 | — | — | CN | disclosed |
| EP-3782991-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | The Scripps Research Institute (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10544136-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-01-28 | — | — | US | disclosed |
| CN-110183348-A | N- (3- nitro -4- alkoxybenzoyl) amino acids, preparation method and its usage | 中国医科大学 | 2019-08-30 | — | — | CN | disclosed |
| US-20190084947-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE | 2019-03-21 | — | — | US | disclosed |
| US-9975863-B2 | Modulators of sphingosine phosphate receptors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-22 | — | — | US | disclosed |
| CN-108017543-A | A kind of preparation method of 3- nitros -4- propoxy benzoic acids | 山东诚汇双达药业有限公司 | 2018-05-11 | — | — | CN | disclosed |
| US-20180009770-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE | 2018-01-11 | — | — | US | disclosed |
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| EP-0187231-A2 | Amino phenyl benzothiazoles | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0090777-A1 | Disazo pigments, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| EP-0088726-A1 | Monoazo pigments, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1983-09-14 | — | — | EP | disclosed |
| US-4382136-A | EPOXIDE, LEWIS ACID | BLOUNT DAVID H | 1983-05-03 | — | — | US | disclosed |
| US-4380592-A | Process for the production of polyhydroxy lignin-cellulose silicate polymer | BLOUNT DAVID H (US) | 1983-04-19 | — | — | US | disclosed |
| US-4377674-A | POLYURETHANES; FOAMS; COPOLYMERS; INSULATION | BLOUNT DAVID H | 1983-03-22 | — | — | US | disclosed |
| EP-0001246-B1 | PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES | CASSELLA Aktiengesellschaft (DE) | 1981-02-25 | — | — | EP | disclosed |
| US-4192947-A | REACTING DIAMINO NITROBENZENE WITH NITROBENZOYL CHLORIDE, CYCLIZING ANILIDE IN AQUEOUS ALKALI, REDUCING NITRO GROUPS WITH SULFIDE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-11 | — | — | US | disclosed |
| EP-0001246-A1 | Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles | CASSELLA Aktiengesellschaft (DE) | 1979-04-04 | — | — | EP | disclosed |
| US-3975196-A | Photoconductive charge transfer complex for electrophotography | PITNEY-BOWES, INC. (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544136-B2 | Modulators of sphingosine phosphate receptors | S1PR1, S1PR3, S1PR2 | MAPT 4693/4885GAA 2874/4885PLA2G4B 259/4885 |
| US-20190084947-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | MAPT 4675/4885GAA 3215/4885PLA2G4B 267/4885 |
| US-20180009770-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | MAPT 4538/4885GAA 3402/4885PLA2G4B 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.