Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.74 |
| ▸ | THRA | P10827 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.63 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403163 | 0.97 | PLA2G4B (0.74) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL9626808 | 0.96 | PLA2G4B (0.77) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL7696499 | 0.96 | PLA2G4B (0.77) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL12431954 | 0.96 | PLA2G4B (0.77) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| Hydrochloric Acid SCHEMBL9627735 | 0.95 | PLA2G4B (0.75) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL177201 | 0.93 | PLA2G4B (0.65) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL6208104 | 0.93 | PLA2G4B (0.66) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL223553 | 0.89 | AKR1C3 (0.67) | PLA2G4BTHRATHRBPRSS1HCAR3 | |
| SCHEMBL2056251 | 0.89 | THRA (0.62) | PLA2G4BTHRATHRBPRSS1XDH | |
| SCHEMBL28748773 | 0.88 | THRA (0.61) | PLA2G4BTHRATHRBPRSS1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11147859-A | — | — | None | — | — | JP | disclosed |
| CN-110183348-B | N- (3-nitro-4-alkoxy benzoyl) amino acid compound, preparation method and application thereof | 中国医科大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-110183348-A | N- (3- nitro -4- alkoxybenzoyl) amino acids, preparation method and its usage | 中国医科大学 | 2019-08-30 | — | — | CN | disclosed |
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160052870-A1 | 3-AMIDOBENZAMIDES AND USES THEREOF FOR INCREASING CELLULAR LEVELS OF A3G AND OTHER A3 FAMILY MEMBERS | NORTHWESTERN UNIVERSITY (US) | 2016-02-25 | — | — | US | disclosed |
| WO-2016029136-A1 | 3-AMIDOBENZAMIDES AND USES THEREOF FOR INCREASING CELLULAR LEVELS OF A3G | NORTHWESTERN UNIVERSITY (US) | 2016-02-25 | — | — | WO | disclosed |
| WO-2012053768-A2 | ARYLOXYPHENOXYACETYL-BASED COMPOUND HAVING HIF-1 INHIBITION ACTIVITY, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-26 | — | — | WO | disclosed |
| US-7968550-B2 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2011-06-28 | — | — | US | disclosed |
| CN-100506792-C | Substituted N-aryl heterocycles, method for the production thereof and their use as medicaments | AVENTIS PHARMA GMBH (DE) | 2009-07-01 | — | — | CN | disclosed |
| US-20070207991-A1 | Substituted N-aryl Heterocycles, Process For Their Preparation and Their Use As Medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-7223788-B2 | therapy for eating disorders, anorexigenic agents, antidiabetic agents, reducing weight in mammals, circadian rhythm disease, psychological disorders | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20070043235-A1 | Process for preparing 3-nitro-4-alkoxybenzoic acid | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2007-02-22 | — | — | US | disclosed |
| CN-1809525-A | Process for producing 3-nitro-4-alkoxybenzoic acid | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2006-07-26 | — | — | CN | disclosed |
| CN-1774418-A | Substituted N-arylheterocycles, method for production and use thereof as medicaments | AVENTIS PHARMA GMBH (DE) | 2006-05-17 | — | — | CN | disclosed |
| EP-1621528-A1 | PROCESS FOR PRODUCING 3-NITRO-4-ALKOXYBENZOIC ACID | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| JP-H11147859-A | PRODUCTION OF ALKOXYNITROBENZOIC ACID AND ALKOXYNITROTOLUENE | FUSO CHEMICAL CO LTD | 1999-06-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052870-A1 | 3-AMIDOBENZAMIDES AND USES THEREOF FOR INCREASING CELLULAR LEVELS OF A3G AND OTHER A3 FAMILY MEMBERS | L3MBTL3, AFG3L2, AMPD3 | PLA2G4B 286/4885THRA 2074/4885THRB 2677/4885 |
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | CYP11B2, CYP11B1, CYP1A1 | PLA2G4B 3585/4885THRA 4014/4885THRB 4348/4885 |
| US-20070207991-A1 | Substituted N-aryl Heterocycles, Process For Their Preparation and Their Use As Medicaments | CYP11B2, CYP11B1, NQO1 | PLA2G4B 3604/4885THRA 3985/4885THRB 4200/4885 |
| US-20070043235-A1 | Process for preparing 3-nitro-4-alkoxybenzoic acid | NOS3, NOS1, NOS2 | PLA2G4B 2155/4885THRA 2508/4885THRB 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.