Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403163 | 0.93 | PLA2G4B (0.74) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| SCHEMBL1749792 | 0.93 | PLA2G4B (0.74) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| SCHEMBL12431954 | 0.92 | PLA2G4B (0.77) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| SCHEMBL7696499 | 0.92 | PLA2G4B (0.77) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| SCHEMBL9626808 | 0.92 | PLA2G4B (0.77) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| Hydrochloric Acid SCHEMBL9627735 | 0.91 | PLA2G4B (0.75) | PLA2G4BPRSS1THRATHRBHCAR3 | |
| SCHEMBL5348288 | 0.89 | XDH (0.55) | PLA2G4BPRSS1THRATHRBMAPT | |
| SCHEMBL9258258 | 0.89 | POLB (0.60) | PLA2G4BPRSS1THRATHRBMAPT | |
| SCHEMBL3574447 | 0.89 | AKR1C3 (0.58) | PLA2G4BPRSS1HCAR3CASP6TSHR | |
| SCHEMBL1402203 | 0.88 | MAPT (0.65) | PLA2G4BPRSS1HCAR3CASP6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178190-A | Preparation method of procaine hydrochloride | 广东先强药业有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-116178190-A | Preparation method of procaine hydrochloride | 广东先强药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-110183348-B | N- (3-nitro-4-alkoxy benzoyl) amino acid compound, preparation method and application thereof | 中国医科大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-110183348-A | N- (3- nitro -4- alkoxybenzoyl) amino acids, preparation method and its usage | 中国医科大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-108017543-A | A kind of preparation method of 3- nitros -4- propoxy benzoic acids | 山东诚汇双达药业有限公司 | 2018-05-11 | — | — | CN | disclosed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| US-20070043235-A1 | Process for preparing 3-nitro-4-alkoxybenzoic acid | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2007-02-22 | — | — | US | disclosed |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-10-05 | — | — | US | disclosed |
| CN-1738798-A | Indole derivatives as somatostatin agonists or antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1621528-A1 | PROCESS FOR PRODUCING 3-NITRO-4-ALKOXYBENZOIC ACID | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | PLA2G4B 103/4885PRSS1 1248/4885THRA 1275/4885 |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | SSTR1, SSTR3, NPY1R | PLA2G4B 3412/4885PRSS1 653/4885THRA 89/4885 |
| US-20070043235-A1 | Process for preparing 3-nitro-4-alkoxybenzoic acid | NOS3, NOS1, NOS2 | PLA2G4B 2155/4885PRSS1 3522/4885THRA 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.