Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402309 | 1.00 | HIF1A (0.39) | HIF1AEPAS1AKT1BIDMCL1 | |
| SCHEMBL11574798 | 0.92 | AKT1 (0.40) | AKT1OPRM1OPRD1OPRK1GABRA1 | |
| SCHEMBL29180390 | 0.91 | TRPA1 (0.39) | HIF1AEPAS1AKT1BIDMCL1 | |
| SCHEMBL340912 | 0.90 | BID (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL258767 | 0.90 | BID (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL258691 | 0.90 | BID (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8991619 | 0.88 | HIF1A (0.41) | HIF1AEPAS1AKT1OPRM1OPRD1 | |
| SCHEMBL31564929 | 0.88 | BID (0.41) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11883257 | 0.87 | BID (0.43) | HIF1AEPAS1BIDMCL1BCL2L1 | |
| SCHEMBL11635259 | 0.87 | P4HB (0.35) | HIF1AEPAS1AKT1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292208-B1 | EXTERNAL PREPARATION FOR SKIN | SHISEIDO CO LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| EP-2292208-A1 | EXTERNAL PREPARATION FOR SKIN | Shiseido Company, Ltd. (JP) | 2011-03-09 | — | — | EP | disclosed |