SCHEMBL1402289

SCHEMBL1402289

CC(C)(c1ccc(OC(O)COCCO)cc1)c1ccc(OC(O)COCCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.46
HTT P42858 3/20 0.43
HIF1A Q16665 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
CYP3A4 P08684 2/20 0.41
KMT2A Q03164 6/20 0.39
KDM4E B2RXH2 6/20 0.37
MEN1 O00255 5/20 0.37
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
PSMB1 P20618 1/20 0.35
PSMB5 P28074 1/20 0.35
PSMB2 P49721 1/20 0.35
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 3/20 0.34
TSHR P16473 3/20 0.34
ESR1 P03372 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3875327 0.94 KMT2A (0.47) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL43511 0.84 AR (0.34) ARHTTHIF1ASMN1; SMN2CYP3A4
Di(Hydroxyethyl)Ether SCHEMBL9469008 0.84 AR (0.42) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL15756007 0.83 HIF1A (0.45) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL6047014 0.82 AR (0.33) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL2839388 0.82 AR (0.39) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL14444701 0.81 AR (0.61) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL7062459 0.81 AR (0.51) ARHTTHIF1ASMN1; SMN2CYP3A4
SCHEMBL13037598 0.79 HTT (0.42) ARHTTHIF1ASMN1; SMN2KMT2A
SCHEMBL98301 0.78 RECQL (0.50) HIF1ACYP3A4KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
EP-3351574-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2022-12-21 EP disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
US-11358354-B2 Process for producing plastic lens and apparatus for producing plastic lens MITSUI CHEMICALS, INC. (JP) 2022-06-14 US disclosed
EP-3992224-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP disclosed
EP-3992694-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP disclosed
US-11312857-B2 Polymerizable composition and molded product MITSUI CHEMICALS, INC. (JP) 2022-04-26 US disclosed
US-20220120936-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL HOYA LENS THAILAND LTD. (TH) 2022-04-21 US disclosed
US-20220112327-A1 METHOD FOR PRODUCING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2022-04-14 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed