Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787258 | 0.89 | SMN1; SMN2 (0.54) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL333514 | 0.86 | HIF1A (0.45) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL1402289 | 0.84 | AR (0.46) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL6515056 | 0.80 | ALDH1A1 (0.52) | SMN1; SMN2CYP3A4HTTHIF1AKDM4E | |
| SCHEMBL9457222 | 0.80 | ESR1 (0.59) | ARCYP3A4HTTHIF1AKDM4E | |
| SCHEMBL16378880 | 0.80 | TAS1R3 (0.43) | ARCYP3A4HTTHIF1AKMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL9469009 | 0.80 | SMN1; SMN2 (0.62) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL3875327 | 0.79 | KMT2A (0.47) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL4612178 | 0.79 | SMN1; SMN2 (0.41) | ARSMN1; SMN2CYP3A4HTTHIF1A | |
| SCHEMBL5457352 | 0.78 | SMN1; SMN2 (0.56) | ARSMN1; SMN2CYP3A4HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270383-A | Preparation of aqueous polyurethane dispersions | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |