SCHEMBL43511

SCHEMBL43511

CC(C)(c1ccc(OC(O)COCCO)cc1)c1c(Br)c(Br)c(OC(O)COCCO)c(Br)c1Br

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537777 0.88 HTT (0.34) ARHTTHIF1AKMT2A
SCHEMBL1402289 0.84 AR (0.46) ARSMN1; SMN2HTTHIF1ACYP3A4
SCHEMBL3875327 0.79 KMT2A (0.47) ARSMN1; SMN2HTTHIF1ACYP3A4
SCHEMBL6047014 0.79 AR (0.33) ARSMN1; SMN2HTTHIF1ACYP3A4
SCHEMBL2319455 0.76
SCHEMBL11575799 0.75 CYP3A4 (0.43) SMN1; SMN2HTTCYP3A4KMT2AMEN1
SCHEMBL5424245 0.75 SMN1; SMN2 (0.51) ARSMN1; SMN2HTTCYP3A4KMT2A
SCHEMBL10616774 0.74 KDM4E (0.31) KMT2A
Di(Hydroxyethyl)Ether SCHEMBL9469008 0.70 AR (0.42) ARSMN1; SMN2HTTHIF1ACYP3A4
Di(Hydroxyethyl)Ether SCHEMBL4614305 0.70 ESR1 (0.43) ARSMN1; SMN2CYP3A4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080233395-A1 Flame Retardant Artificial Polyester Hair KANEKA CORPORATION (JP) 2008-09-25 US claimed
EP-1728900-A1 FLAME-RETARDANT ARTIFICIAL POLYESTER HAIR KANEKA CORPORATION (JP) 2006-12-06 EP claimed
US-20040138405-A1 Preparation of bromine-containing hydroxy-functional copolymers SOUTHWEST DISTRIBUTING COMPANY 2004-07-15 US claimed
EP-1379571-A1 PREPARATION OF BROWMINE-CONTAINING HYDROXY-FUNCTIONAL COPOLYMERS Southwest Distributing Co. (US) 2004-01-14 EP claimed
US-6600007-B2 Preparation of bromine-containing hydroxy-functional copolymers SOUTHWEST DISTRIBUTING CO. 2003-07-29 US claimed
WO-2002077061-A1 PREPARATION OF BROWMINE-CONTAINING HYDROXY-FUNCTIONAL COPOLYMERS SOUTHWEST DISTRIBUTING CO. (US) 2002-10-03 WO claimed
US-20020143139-A1 PREPARATION OF BROMINE-CONTAINING HYDROXY-FUNCTIONAL COPOLYMERS TRI-ISO, INC. 2002-10-03 US claimed
EP-0606832-B1 Radiopaque polyurethanes BAYER AG (US) 1998-04-08 EP claimed
WO-2024150602-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE FORMED OF SAME 帝人株式会社 2024-07-18 WO disclosed
US-12031241-B2 Core-sheath composite fiber for artificial hair, headdress product including same, and production method therefor KANEKA CORPORATION (JP) 2024-07-09 US disclosed
WO-2024101409-A1 HEAT-RESISTANT CONTAINER AND COOKING METHOD 株式会社細川洋行 2024-05-16 WO disclosed
WO-2024070342-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2024-04-04 WO disclosed
US-20240108091-A1 CORE-SHEATH CONJUGATE FIBER FOR ARTIFICIAL HAIR, HAIR ORNAMENT INCLUDING SAME, AND METHOD FOR PRODUCING SAME KANEKA CORPORATION (JP) 2024-04-04 US disclosed
US-20240069438-A1 PHOTO-CURABLE COMPOSITION AND METHODS FOR PREPARING CURED FILM, OPTICAL COMPONENT, CIRCUIT SUBSTRATE, ELECTRICAL COMPONENT AND REPLICA MOLD USING THE SAME CANON KK (JP) 2024-02-29 US disclosed
US-4954551-A BISMUTH, ANTIMONY CONTAINING FLAME RETARDANTS FOR THERMOPLASTICS ETHYL CORPORATION (US) 1990-09-04 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
US-4560719-A BLENDS WITH POLYSILOXANE, ALUMINUM AND/OR MAGNESIUM HYDROXIDE, ZINC AND/OR MANGANESE CARBONATE, RED PHOSPHORUS AND/OR BROMINE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1985-12-24 US disclosed