Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848708 | 0.86 | TSHR (0.65) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL2567389 | 0.84 | TSHR (0.54) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL2567392 | 0.84 | TSHR (0.54) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL6247713 | 0.84 | TSHR (0.54) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL15143051 | 0.83 | LTA4H (0.56) | LNPEPERAP2 | |
| Hydrochloric Acid SCHEMBL6898149 | 0.83 | TSHR (0.53) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL14444028 | 0.83 | POLB (0.55) | METAP2KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL27559888 | 0.83 | TSHR (0.53) | TSHRMETAP2METAP1LNPEPANPEP | |
| SCHEMBL3291656 | 0.82 | TSHR (0.51) | TSHRMETAP2METAP1ANPEPERAP1 | |
| SCHEMBL1736260 | 0.81 | ALPI (0.66) | ANPEPCTSCKMT2ACTSDALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024095177-A1 | MANGANESE BIFUNCTIONAL CHELATING AGENT CONJUGATION PLATFORM FOR TARGETED MR IMAGING | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-05-10 | — | — | WO | disclosed |
| WO-2008141189-A1 | GHRELIN MODULATING COMPOUNDS AND COMBINATIONS THEREOF | ELIXIR PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |