SCHEMBL1736260

SCHEMBL1736260

NNC(=O)C(N)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.66
PKM P14618 1/20 0.66
PTGS1 P23219 1/20 0.66
XIAP P98170 1/20 0.66
SLC7A5 Q01650 1/20 0.66
SLC15A1 P46059 1/20 0.61
CTSC P53634 1/20 0.59
LTA4H P09960 1/20 0.57
SLC1A3 P43003 2/20 0.51
SLC1A2 P43004 2/20 0.51
SLC1A1 P43005 2/20 0.51
MMP2 P08253 1/20 0.51
KMT2A Q03164 1/20 0.51
HDAC8 Q9BY41 2/20 0.50
CTSD P07339 1/20 0.50
ANPEP P15144 1/20 0.49
RNPEP Q9H4A4 1/20 0.49
DNPEP Q9ULA0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6423222 1.00 ALPI (0.66) ALPIPKMPTGS1XIAPSLC7A5
Bromide SCHEMBL11103045 0.98 ALPI (0.63) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL11100486 0.87 KMT2A (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL17844273 0.86 ALPI (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5097140 0.85 CTSC (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1803032 0.85 ALPI (0.66) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2512478 0.85 ALPI (0.66) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1168389 0.85 ALPI (0.66) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL11102597 0.83 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL989802 0.83 SLC7A5 (0.63) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0989982-B1 BARBITURIC ACID DERIVATIVES WITH ANTIMETASTATIC AND ANTITUMOR ACTIVITY ROCHE DIAGNOSTICS GMBH (DE) 2005-08-17 EP claimed
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
US-20200352917-A1 MEDICATED SPRAY FOR TREATMENT OF SUBSTANCE ABUSE, OVERDOSE, ADDICTION AND IMPULSE CONTROL DISORDERS GOOBERMAN LANCE L (US) 2020-11-12 US disclosed
EP-3042718-A1 DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2016-07-13 EP disclosed
US-20160122686-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-05-05 US disclosed
EP-2585420-B1 METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-04-06 EP disclosed
US-9127233-B2 Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification Dietz, Ulrich (DE) 2015-09-08 US disclosed
EP-2585420-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2013-05-01 EP disclosed
US-20130090488-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2013-04-11 US disclosed
WO-2011160857-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2011-12-29 WO disclosed
EP-0126088-A1 ARYL SUBSTITUTED 7-OXABICYCLOHEPTANE COMPOUNDS E.R. SQUIBB & SONS, INC. (US) 1984-11-28 EP disclosed
US-4463015-A Aryl substituted 7-oxabicycloheptane compounds, useful in inhibiting platelet aggregation E. R. SQUIBB & SONS, INC. (US) 1984-07-31 US disclosed
US-4438249-A Biodegradable polyurethane urea acyl semicarbazides for the manufacture of biodegradable alloimplants LIPATOVA TATYANA E (SU) 1984-03-20 US disclosed
WO-1984000754-A1 ARYL SUBSTITUTED 7-OXABICYCLOHEPTANE COMPOUNDS SQUIBB & SONS INC (US) 1984-03-01 WO disclosed
EP-0094792-A1 7-Oxabicycloheptane substituted amino prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1983-11-23 EP disclosed
US-4416896-A 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease E. R. SQUIBB & SONS, INC. (US) 1983-11-22 US disclosed
US-4339534-A USING A CARBOXYPEPTIDASE ENZYME; ENZYMES/HYDROLASES/; PROTEOLYTIC ENZYMES; DEESTERIFICATION, AMIDATION; CLEAVAGE/C-N/; DE FORENEDE BRYGGERIER A/S (DK) 1982-07-13 US disclosed
WO-1980002157-A1 A PROCESS FOR ENZYMATIC PRODUCTION OF PEPTIDES FORENEDE BRYGGERIER AS (DK) 1980-10-16 WO disclosed
EP-0017485-A1 A process for enzymatic production of peptides DE FORENEDE BRYGGERIER A/S (DK) 1980-10-15 EP disclosed
US-3956260-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA ALPI 1995/4885PKM 2844/4885PTGS1 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.