⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059207 | 0.79 | — | — | |
| SCHEMBL12658636 | 0.79 | — | — | |
| SCHEMBL1405881 | 0.77 | — | — | |
| SCHEMBL440540 | 0.77 | — | — | |
| SCHEMBL1970431 | 0.77 | — | — | |
| SCHEMBL641808 | 0.77 | — | — | |
| SCHEMBL13627004 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3303102 | 0.76 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL2144598 | 0.76 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL4431863 | 0.76 | KDM4E (0.96) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3833665-B1 | DIAZABICYCLOOCTANONES AS INHIBITORS OF SERINE BETA-LACTAMASES | ANTABIO SAS (FR) | 2023-07-19 | — | — | EP | disclosed |
| EP-2931723-B1 | NEW BICYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND -LACTAMASE INHIBITORS | FEDORA PHARMACEUTICALS INC (CA) | 2020-08-26 | — | — | EP | disclosed |
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| WO-2008140792-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2008-11-20 | — | — | WO | disclosed |