Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 6/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | HEXA | P06865 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24813700 | 0.94 | STAT3 (0.57) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL16557129 | 0.92 | MEN1 (0.53) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL16558635 | 0.92 | MEN1 (0.53) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL14023201 | 0.89 | KDM4E (0.55) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL16558636 | 0.87 | STAT3 (0.55) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL16557130 | 0.87 | STAT3 (0.55) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL918303 | 0.86 | TDP1 (0.51) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL3670226 | 0.84 | TDP1 (0.50) | MEN1KMT2ARAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL2284215 | 0.84 | TDP1 (0.50) | MEN1KMT2ARAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL13913061 | 0.83 | KDM4E (0.67) | KDM4EMEN1KMT2ARGS12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990372-A2 | Water soluble UV filters | Ciba Holding Inc. (CH) | 2008-11-12 | — | — | EP | disclosed |