Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.45 |
| ▸ | HEXA | P06865 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14024117 | 0.90 | KDM4E (0.46) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL14023220 | 0.89 | KDM4E (0.61) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL92104 | 0.87 | TERT (0.54) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL32689773 | 0.87 | TERT (0.54) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL13883925 | 0.85 | TERT (0.48) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL496740 | 0.85 | GLS (0.53) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1566949 | 0.84 | HEXA (0.66) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL24813700 | 0.83 | STAT3 (0.57) | KDM4EMEN1KMT2ARGS12NPC1 | |
| SCHEMBL27564703 | 0.83 | HEXA (0.64) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL6284185 | 0.83 | GLS (0.52) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990372-A2 | Water soluble UV filters | Ciba Holding Inc. (CH) | 2008-11-12 | — | — | EP | disclosed |