SCHEMBL24813700

SCHEMBL24813700

O=C1c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C(=O)N1CCCS(=O)(=O)O)c64)C(=O)N(CCCS(=O)(=O)O)C5=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.57
HIF1A Q16665 1/20 0.57
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
RGS12 O14924 1/20 0.54
NPC1 O15118 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
PABPC1 P11940 1/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TERT O14746 7/20 0.53
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
PIN1 Q13526 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14023220 0.94 KDM4E (0.61) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL16558636 0.93 STAT3 (0.55) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL16557130 0.93 STAT3 (0.55) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL16557129 0.86 MEN1 (0.53) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL16558635 0.86 MEN1 (0.53) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL92104 0.85 TERT (0.54) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL32689773 0.85 TERT (0.54) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL14023201 0.83 KDM4E (0.55) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL14604449 0.83 STAT3 (0.56) STAT3HIF1AKDM4EMEN1KMT2A
SCHEMBL13883925 0.82 TERT (0.48) STAT3HIF1AKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022270182-A1 POSITIVE PHOTOSENSITIVE PIGMENT COMPOSITION, CURED FILM CONTAINING CURED PRODUCT THEREOF, AND ORGANIC EL DISPLAY DEVICE 東レ株式会社 2022-12-29 WO disclosed