Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418534 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL15485079 | 0.81 | MEN1 (0.57) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 | |
| SCHEMBL29802336 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL3540096 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL15485248 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL28967047 | 0.79 | USP2 (0.45) | ALDH1A1LMNAHPGDKDM4EGLA | |
| Hydrochloric Acid SCHEMBL17592286 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL14023403 | 0.78 | KDM4E (0.58) | ALDH1A1LMNAKDM4EGAACYP1A2 | |
| SCHEMBL20412731 | 0.78 | HTT (0.58) | ALDH1A1LMNAHPGDKDM4EGLA | |
| SCHEMBL2747362 | 0.78 | MAP4K4 (0.54) | ALDH1A1LMNAKDM4EUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701670-B2 | Pyrazolyl-ureas as kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| EP-2885284-B1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | RESPIVERT LTD (GB) | 2016-11-02 | — | — | EP | disclosed |
| CN-105073725-A | Pyrazolyl-ureas as kinase inhibitors | RESPIVERT LTD | 2015-11-18 | — | — | CN | disclosed |
| US-20150218137-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| EP-2885284-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | Respivert Limited (GB) | 2015-06-24 | — | — | EP | disclosed |
| US-20140057915-A1 | KINASE INHIBITORS | TOPIVERT PHARMA LIMITED (GB) | 2014-02-27 | — | — | US | disclosed |
| WO-2014027209-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-02-20 | — | — | WO | disclosed |
| WO-2008140420-A2 | PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218137-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | SYK, BTK, LYN | ALDH1A1 3817/4885LMNA 4618/4885HPGD 3014/4885 |
| US-20140057915-A1 | KINASE INHIBITORS | SYK, BTK, LYN | ALDH1A1 3858/4885LMNA 4609/4885HPGD 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.