Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542006 | 0.79 | EPHX2 (0.51) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14023398 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1CYP2C19GAASIGMAR1 | |
| SCHEMBL23139634 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14334458 | 0.74 | KDM4E (1.00) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23786329 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3543155 | 0.73 | CYP2D6 (0.52) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14500184 | 0.72 | NPC1 (0.50) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3541043 | 0.71 | HTR4 (0.45) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3115266 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15485079 | 0.71 | MEN1 (0.57) | KDM4EALDH1A1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140420-A2 | PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2008-11-20 | — | — | WO | disclosed |