Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966017 | 0.85 | MAOA (0.44) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL19163783 | 0.77 | HRH3 (0.33) | HRH3 | |
| SCHEMBL15932774 | 0.67 | MAOA (0.56) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL5549793 | 0.67 | MAOA (0.50) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL2589239 | 0.66 | — | — | |
| SCHEMBL9963163 | 0.66 | LRRK2 (0.36) | HRH3 | |
| SCHEMBL10512470 | 0.65 | MAOA (0.44) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL15828432 | 0.64 | SIGMAR1 (0.33) | — | |
| SCHEMBL19171272 | 0.64 | CHRM3 (0.39) | MAOAMAOBCHRM3 | |
| SCHEMBL14970401 | 0.63 | NOTUM (0.50) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132162-A1 | 3- (SULPHONYLAMINO) -PHENYL-2 -HYDROXY-ETHYLAMINO DERIVATIVES USEFUL AS BETA-AGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-06 | — | — | WO | disclosed |