Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14024028 | 0.79 | BCL2L1 (0.33) | DPP4SLC6A4 | |
| SCHEMBL11445604 | 0.77 | SLC18A3 (0.50) | HTR2CSLC18A3SIGMAR1QDPRHTR3A | |
| SCHEMBL25359337 | 0.76 | SLC7A5 (0.53) | SLC18A3SIGMAR1SLC6A3 | |
| SCHEMBL25359343 | 0.76 | SLC7A5 (0.53) | SLC18A3SIGMAR1SLC6A3 | |
| Hydrochloric Acid SCHEMBL11436401 | 0.76 | HTR2C (0.49) | HTR2CSLC18A3SIGMAR1QDPRHTR3A | |
| SCHEMBL19062853 | 0.75 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL14024059 | 0.75 | SLC18A3 (0.39) | SLC18A3SIGMAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27489026 | 0.74 | SLC18A3 (0.55) | HTR2CSLC18A3SIGMAR1QDPRHTR3A | |
| SCHEMBL14023889 | 0.74 | GAA (0.34) | SLC6A4 | |
| SCHEMBL19062611 | 0.72 | ADRB1 (0.46) | SIGMAR1DPP4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |