Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023889 | 0.92 | GAA (0.34) | BCL2L1MCL1SLC6A4NMT1GAA | |
| SCHEMBL14023969 | 0.79 | HTR2C (0.46) | SLC6A4DPP4 | |
| SCHEMBL14025103 | 0.73 | KDM4E (0.45) | DPP4DPP7LMNAKMT2A | |
| SCHEMBL12603830 | 0.73 | CYP1A2 (0.43) | GAALMNAKMT2ASMN1; SMN2SPHK1 | |
| SCHEMBL14024059 | 0.72 | SLC18A3 (0.39) | SLC6A4 | |
| SCHEMBL19062853 | 0.72 | SLC6A4 (0.32) | SLC6A4EPHX1 | |
| SCHEMBL3086027 | 0.70 | SLC18A3 (0.41) | SOS1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14023961 | 0.70 | RORC (0.44) | LMNAKMT2A | |
| SCHEMBL17186386 | 0.69 | SPHK1 (0.40) | BCL2L1MCL1SLC6A4SPHK1 | |
| SCHEMBL14024010 | 0.69 | SLC6A4 (0.31) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |