Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025121 | 0.81 | MAPT (0.40) | CDK2AKT1SLC6A4EPHX1 | |
| SCHEMBL14023917 | 0.79 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL17297768 | 0.78 | USP1 (0.41) | WNT3AUSP1WDR48HPGDSIDO1 | |
| SCHEMBL4750423 | 0.78 | CYP2A6 (0.58) | CYP2A6 | |
| SCHEMBL14024057 | 0.78 | CYP2A6 (0.58) | CYP2A6 | |
| SCHEMBL14642358 | 0.78 | WNT3A (0.44) | WNT3AUSP1WDR48PIK3CDPIK3CA | |
| SCHEMBL1998077 | 0.76 | SLC7A5 (0.53) | PTGS2 | |
| SCHEMBL2435448 | 0.76 | CSNK1E (0.42) | CDK2AKT1USP1WDR48PI4KB | |
| SCHEMBL13790816 | 0.74 | CYP2A6 (0.56) | WNT3APIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL19062888 | 0.74 | HRH3 (0.56) | SLC6A4CYP2A6EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |