Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18828829 | 0.82 | TP53 (0.33) | TDP1TP53CYP1A2CYP2A6 | |
| SCHEMBL17635973 | 0.78 | TP53 (0.33) | TDP1TP53CYP1A2CYP2A6 | |
| SCHEMBL16152376 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL257640 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18926958 | 0.70 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL14154962 | 0.68 | NOS3 (0.34) | — | |
| SCHEMBL23181976 | 0.65 | UHRF1 (0.35) | CYP1A2CYP2A6 | |
| SCHEMBL17071904 | 0.63 | CYP2A6 (0.33) | TDP1TP53CYP3A4THRBALOX15 | |
| SCHEMBL8346103 | 0.63 | CD44 (0.30) | CYP1A2CYP2A6 | |
| SCHEMBL10077289 | 0.63 | CD44 (0.30) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008136815-A2 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | SCHERING CORPORATION (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008082484-A1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |