Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 11/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583904 | 1.00 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1LMNAHPGDHTT | |
| SCHEMBL18570253 | 0.84 | CA12 (0.35) | L3MBTL1ALDH1A1LMNAHPGDHTT | |
| SCHEMBL21276638 | 0.81 | CA12 (0.33) | L3MBTL1ALDH1A1CA12CA2CA9 | |
| SCHEMBL14427457 | 0.80 | CA12 (0.31) | CA12CA2CA9 | |
| SCHEMBL19718545 | 0.79 | CA12 (0.32) | CA12CA2CA9RAB9A | |
| SCHEMBL22481904 | 0.78 | CA12 (0.32) | CA12CA2CA9RAB9A | |
| SCHEMBL20216019 | 0.73 | RECQL (0.41) | ALDH1A1HPGDRAB9A | |
| SCHEMBL23739389 | 0.71 | CYP3A4 (0.41) | L3MBTL1ALDH1A1LMNAHTTGRIN2D | |
| SCHEMBL12957563 | 0.71 | MAPT (0.48) | L3MBTL1ALDH1A1LMNAHPGDHTT | |
| SCHEMBL13891036 | 0.71 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008136815-A2 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | SCHERING CORPORATION (US) | 2008-11-13 | — | — | WO | disclosed |