Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025493 | 0.92 | KMT2A (0.62) | LSSSMN1; SMN2USP2LMNATSHR | |
| SCHEMBL14025511 | 0.89 | LMNA (0.56) | LSSSMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL14025495 | 0.89 | TSHR (0.60) | SMN1; SMN2LMNATSHRPOLBALDH1A1 | |
| SCHEMBL14025508 | 0.87 | LMNA (0.55) | LSSSMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL14025498 | 0.87 | TSHR (0.63) | SMN1; SMN2USP2LMNATSHRALDH1A1 | |
| SCHEMBL14025510 | 0.86 | LSS (0.55) | LSSSMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL14025679 | 0.85 | ALDH1A1 (0.55) | MC4RPOLBHTR6ALDH1A1 | |
| SCHEMBL14025499 | 0.85 | LSS (0.60) | LSSSMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL14025502 | 0.85 | TSHR (0.50) | SMN1; SMN2LMNATSHRL3MBTL1POLB | |
| SCHEMBL14068492 | 0.85 | TSHR (0.67) | SMN1; SMN2LMNATSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261978-A1 | treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea | METASTATIX, INC. | 2008-10-23 | — | — | US | disclosed |
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261978-A1 | treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea | MKI67, CCNI, CDKN1A | LSS 2842/4885SMN1; SMN2 3131/4885USP2 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.