SCHEMBL14026664

SCHEMBL14026664

CC1CCCCCCCCCCCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 1/20 0.42
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
HSD17B10 Q99714 1/20 0.35
CA12 O43570 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
SHBG P04278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675505 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
Cyclohexane SCHEMBL3670822 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
SCHEMBL802 1.00
SCHEMBL5189 1.00
SCHEMBL9256078 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
Cycloheptane SCHEMBL23885013 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
SCHEMBL7912061 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
SCHEMBL15121491 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
SCHEMBL9791506 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2
SCHEMBL866985 1.00 ACHE (0.43) ACHEKMT2AEPHX1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020204188-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER ポリプラスチックス株式会社 2020-10-08 WO disclosed
CN-107112366-B Organic thin film transistor 日本曹达株式会社 2020-07-10 CN disclosed
US-20200179914-A1 METHOD FOR PRODUCING CATALYST POLYPLASTICS CO., LTD. (JP) 2020-06-11 US disclosed
WO-2020071494-A1 METHOD FOR PRODUCING CYCLIC OLEFIN POLYMER ポリプラスチックス株式会社 2020-04-09 WO disclosed
EP-2617746-B1 NOVEL COPOLYMER NIPPON SODA CO (JP) 2018-01-10 EP disclosed
WO-2017079718-A1 METHODS OF FORMING AROMATIC CONTAINING COMPOUNDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2017-05-11 WO disclosed
US-20150166528-A1 Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests BASF SE (DE) 2015-06-18 US disclosed
US-9018311-B2 Copolymer NIPPON SODA CO., LTD. (JP) 2015-04-28 US disclosed
US-8791142-B2 Oxazole pyridine derivatives useful as S1P1 receptor agonists MERCK SERONO S.A. (CH) 2014-07-29 US disclosed
US-20130217832-A1 NOVEL COPOLYMER NIPPON SODA CO., LTD. (JP) 2013-08-22 US disclosed
EP-2617746-A1 NOVEL COPOLYMER Nippon Soda Co., Ltd. (JP) 2013-07-24 EP disclosed
US-20110306636-A1 OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS MERCK SERONO SA (CH) 2011-12-15 US disclosed
CN-101534904-A BCL inhibitors for the treatment of platelet excess ABBOTT LAB (US) 2009-09-16 CN disclosed
US-7449542-B2 Polymers XEROX CORPORATION (US) 2008-11-11 US disclosed
US-20070093641-A1 POLYMERS XEROX CORPORATION 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166528-A1 Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests PTMS, PDXK, TH ACHE 10/4885KMT2A 2849/4885EPHX1 1683/4885
US-20110306636-A1 OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS S1PR1, S1PR3, S1PR5 ACHE 3451/4885KMT2A 3880/4885EPHX1 779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.