Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987665 | 0.94 | OPRM1 (0.42) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2980170 | 0.91 | OPRM1 (0.44) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2990445 | 0.90 | OPRK1 (0.43) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2987566 | 0.90 | OPRK1 (0.43) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2990447 | 0.90 | OPRK1 (0.43) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2990244 | 0.90 | OPRK1 (0.43) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL14026651 | 0.90 | OPRK1 (0.43) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2992902 | 0.90 | OPRK1 (0.41) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2992073 | 0.89 | OPRM1 (0.44) | OPRK1OPRM1OPRD1KCNH2GRIN2D | |
| SCHEMBL2990096 | 0.89 | OPRK1 (0.42) | OPRK1OPRM1OPRD1KCNH2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008142454-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | WO | disclosed |