Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21263555 | 0.92 | MME (0.52) | SIGMAR1MMEACECPA1ACE2 | |
| SCHEMBL23306933 | 0.92 | MME (0.52) | SIGMAR1MMEACECPA1ACE2 | |
| SCHEMBL27268141 | 0.89 | HDAC3 (0.51) | SIGMAR1ALDH1A1POLBCTSSCTSK | |
| SCHEMBL30699914 | 0.88 | SIGMAR1 (0.53) | SIGMAR1POLBATMNPC1RAB9A | |
| SCHEMBL989835 | 0.88 | SIGMAR1 (0.53) | SIGMAR1POLBATMNPC1RAB9A | |
| SCHEMBL4672507 | 0.88 | SIGMAR1 (0.53) | SIGMAR1POLBATMNPC1RAB9A | |
| SCHEMBL22630552 | 0.88 | PPARG (0.46) | SIGMAR1ALDH1A1RAB9A | |
| SCHEMBL22106249 | 0.88 | PPARG (0.46) | SIGMAR1ALDH1A1RAB9A | |
| SCHEMBL7271174 | 0.87 | SIGMAR1 (0.56) | SIGMAR1NAALAD2MMEACECPA1 | |
| SCHEMBL839840 | 0.87 | SIGMAR1 (0.56) | SIGMAR1NAALAD2MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449544-B2 | p21 peptides | CYCLACEL LIMITED (GB) | 2008-11-11 | — | — | US | disclosed |