Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699914 | 1.00 | SIGMAR1 (0.53) | SIGMAR1EPHX1FCER2MMP1POLB | |
| SCHEMBL4672507 | 1.00 | SIGMAR1 (0.53) | SIGMAR1EPHX1FCER2MMP1POLB | |
| SCHEMBL14027140 | 0.88 | SIGMAR1 (0.55) | SIGMAR1POLBATMACENPC1 | |
| SCHEMBL990139 | 0.87 | SIGMAR1 (0.56) | SIGMAR1EPHX1FCER2MMP1POLB | |
| SCHEMBL10748039 | 0.87 | SIGMAR1 (0.56) | SIGMAR1EPHX1FCER2MMP1POLB | |
| SCHEMBL7271174 | 0.86 | SIGMAR1 (0.56) | SIGMAR1ACENAALAD2 | |
| SCHEMBL839840 | 0.86 | SIGMAR1 (0.56) | SIGMAR1ACENAALAD2 | |
| SCHEMBL1958454 | 0.86 | SIGMAR1 (0.56) | SIGMAR1ACENAALAD2 | |
| SCHEMBL13910050 | 0.85 | ACE (0.52) | CA12CA1CA9ACESLC7A5 | |
| SCHEMBL12118797 | 0.85 | ATM (0.44) | EPHX1ATMACENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSTY | 2023-01-26 | — | — | US | disclosed |
| EP-3569252-B1 | ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS | UNIV OREGON STATE (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2021087082-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021087083-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-2861581-B9 | 1,2,3,4-Tetrahydroisoquinoline-pyrrolidine derivatives as antagonists of apoptosis (IAPs) for the treatment of cancer. | BRISTOL MYERS SQUIBB CO (US) | 2017-08-30 | — | — | EP | disclosed |
| US-9255062-B2 | Fatty acid derivatives for oral administration endowed with high palatability | RHEA INNOVATIONS S.R.L. (IT) | 2016-02-09 | — | — | US | disclosed |
| CN-102105436-B | Oral fatty acid derivatives endowed with high palatability | BERNI CANANI ROBERTO | 2014-11-12 | — | — | CN | disclosed |
| CN-102105436-A | Oral fatty acid derivatives endowed with high palatability | ROBERTO BERNI CANANI | 2011-06-22 | — | — | CN | disclosed |
| US-20110098319-A1 | FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY | RHEA INNOVATIONS S.R.L. (IT) | 2011-04-28 | — | — | US | disclosed |
| EP-2268605-A1 | FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PAIA- TABILITY | Berni Canani, Roberto (IT) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009130735-A1 | FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY | BERNI CANANI ROBERTO (IT) | 2009-10-29 | — | — | WO | disclosed |
| EP-1409688-A2 | NUCLEIC ACID SEQUENCES ENCODING ENANTIOSELECTIVE AMIDASES | DSM IP Assets B.V. (NL) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010312-A2 | NUCLEIC ACID SEQUENCES ENCODING ENANTIOSELECTIVE AMIDASES | DSM IP ASSETS B.V. (NL) | 2003-02-06 | — | — | WO | disclosed |
| EP-0495013-B1 | HEXAPEPTIDES WITH SULPHATE ESTER GROUPS | FISONS CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0226217-B1 | Peptides with sulfate ester group | FISONS CORP (US) | 1994-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098319-A1 | FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY | FABP2, FFAR2, VIP | SIGMAR1 2001/4885EPHX1 4011/4885FCER2 1416/4885 |
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | LRBA, HADHA, IMPDH1 | SIGMAR1 4861/4885EPHX1 2056/4885FCER2 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.