Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889472 | 0.87 | HTR2C (0.34) | SLC6A4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10216634 | 0.77 | PRCP (0.36) | MEN1KMT2AIDH1PRCPALDH1A1 | |
| SCHEMBL176699 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2APRCPALDH1A1HTT | |
| SCHEMBL13889388 | 0.70 | MEN1 (0.43) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL13871545 | 0.69 | CNR1 (0.43) | CYP2D6MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3467155 | 0.67 | MEN1 (0.42) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL14027861 | 0.66 | — | — | |
| SCHEMBL13871616 | 0.66 | CNR1 (0.37) | MEN1KMT2AALDH1A1SMYD3CRHBP | |
| SCHEMBL13871552 | 0.65 | CNR1 (0.43) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13889471 | 0.65 | CNR1 (0.43) | ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |