Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871668 | 0.88 | ALDH1A1 (0.45) | PRCPMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL176699 | 0.85 | ALDH1A1 (0.46) | PRCPMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL300346 | 0.78 | KCNQ3 (0.39) | PRCPKCNQ3KCNQ2ALDH1A1MAPK1 | |
| SCHEMBL13871545 | 0.77 | CNR1 (0.43) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL14027872 | 0.77 | CYP2D6 (0.32) | PRCPMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3467155 | 0.75 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL13889389 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1IDH1 | |
| SCHEMBL13871616 | 0.73 | CNR1 (0.37) | MEN1KMT2AALDH1A1LMNASMYD3 | |
| SCHEMBL13871552 | 0.72 | CNR1 (0.43) | ALDH1A1 | |
| SCHEMBL13889471 | 0.72 | CNR1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735286-B1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-04 | — | — | EP | disclosed |