Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028196 | 0.92 | KMO (0.43) | KMOCNR2NOD1NOD2CDK4 | |
| SCHEMBL14541171 | 0.91 | KMO (0.38) | KMOCNR2NOD1NOD2CDK4 | |
| SCHEMBL14028207 | 0.87 | KMO (0.42) | KMOCNR2NOD1NOD2CDK4 | |
| SCHEMBL14028199 | 0.85 | KMO (0.46) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14028849 | 0.83 | KMO (0.42) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14028851 | 0.83 | KMO (0.38) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14028850 | 0.83 | KMO (0.38) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14028798 | 0.83 | KMO (0.43) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14028391 | 0.83 | KMO (0.43) | KMOCNR2CDK4CCND3GSK3B | |
| SCHEMBL14541179 | 0.83 | KMO (0.35) | KMOCNR2NOD1NOD2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080279829-A1 | Phenyl-(4-Phenyl-Pyrimidin-2-Yl)-Amines For Enhancing Immunotolerance | WOISETSCHLAEGER MAXIMILIAN | 2008-11-13 | — | — | US | disclosed |
| WO-2007039216-A1 | PHENYL-(4-PHENYL-PYRIMIDIN-2-YL)-AMINES FOR ENHANCING IMMUNOTOLERANCE | NOVARTIS AG (CH) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279829-A1 | Phenyl-(4-Phenyl-Pyrimidin-2-Yl)-Amines For Enhancing Immunotolerance | IFNG, IL2, LY96 | KMO 716/4885CNR2 462/4885NOD1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.