Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046518 | 0.89 | SGMS2 (0.53) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL14339764 | 0.89 | SGMS2 (0.53) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL14028219 | 0.85 | SGMS2 (0.55) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL6949956 | 0.82 | SGMS2 (0.55) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL6949961 | 0.82 | SGMS2 (0.55) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL14003834 | 0.82 | SGMS2 (0.55) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL11086253 | 0.80 | NPC1 (0.60) | SGMS2GAANPC1HTTMEN1 | |
| Water SCHEMBL11090686 | 0.79 | NPC1 (0.58) | SGMS2GAANPC1HTTMEN1 | |
| SCHEMBL21247830 | 0.77 | MAOB (0.61) | NPC1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL30468871 | 0.77 | SGMS2 (0.67) | SGMS2GAANPC1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |