SCHEMBL11086253

SCHEMBL11086253

O=CC(=O)c1ccccc1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.60
SGMS2 Q8NHU3 4/20 0.59
HTT P42858 1/20 0.56
GAA P10253 1/20 0.55
PARP1 P09874 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
KDM4E B2RXH2 1/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CCNB2 O95067 1/20 0.51
CDK1 P06493 1/20 0.51
CDK4 P11802 1/20 0.51
CCNB1 P14635 1/20 0.51
CCND1 P24385 1/20 0.51
CCNB3 Q8WWL7 1/20 0.51
PTGER1 P34995 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11090686 0.98 NPC1 (0.58) NPC1SGMS2HTTGAAPARP1
SCHEMBL14028219 0.83 SGMS2 (0.55) NPC1SGMS2HTTGAAPARP1
SCHEMBL6949956 0.83 SGMS2 (0.55) NPC1SGMS2HTTGAAPARP1
SCHEMBL6949961 0.83 SGMS2 (0.55) NPC1SGMS2HTTGAAPARP1
SCHEMBL9696207 0.82 SGMS2 (0.66) NPC1SGMS2HTTGAAPARP1
SCHEMBL112903 0.82 SGMS2 (0.66) NPC1SGMS2HTTGAAPARP1
SCHEMBL29433417 0.82 SGMS2 (0.66) NPC1SGMS2HTTGAAPARP1
SCHEMBL9231981 0.81 SGMS2 (0.54) NPC1SGMS2HTTGAAPARP1
SCHEMBL658207 0.81 ABCG2 (0.57) SGMS2LMNAMAPTPTGER1PTGER4
SCHEMBL658208 0.81 ABCG2 (0.57) SGMS2LMNAMAPTPTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490392-A Benzylalcohol derivative and process for preparing TANABE SEIYAKU CO., LTD. (JP) 1984-12-25 US disclosed
US-4218479-A Novel benzylalcohols and pharmaceutical compositions and use thereof TANABE SEIYAKU CO., LTD. (JP) 1980-08-19 US disclosed