SCHEMBL14028641

SCHEMBL14028641

COOC(=O)CCN(C)CCC(=O)OOC

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
KDM5A P29375 2/20 0.39
TSHR P16473 2/20 0.36
DNM1 Q05193 1/20 0.33
LTA4H P09960 6/20 0.33
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5788270 0.80 KMT2A (0.95) KMT2AMEN1KDM5ATSHRLTA4H
SCHEMBL10211 0.79 TSHR (0.56) KMT2AMEN1TSHRKDM6BKDM5C
SCHEMBL15314279 0.78 KMT2A (0.91) KMT2AMEN1KDM5ATSHRLTA4H
SCHEMBL26697234 0.77 DNM1 (0.43) KMT2AMEN1KDM5ATSHRDNM1
SCHEMBL26696662 0.76 DNM1 (0.46) KMT2AMEN1KDM5ATSHRDNM1
SCHEMBL21381223 0.74 KMT2A (0.83) KMT2AMEN1KDM5ATSHRLTA4H
SCHEMBL25801006 0.74 KMT2A (0.83) KMT2AMEN1KDM5ATSHRLTA4H
SCHEMBL27383480 0.74 MEN1 (0.83) KMT2AMEN1KDM5ATSHRLTA4H
SCHEMBL4788929 0.73 MEN1 (0.60) KMT2AMEN1KDM5ATSHRDNM1
SCHEMBL15781627 0.73 KMT2A (0.79) KMT2AMEN1KDM5ATSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7432239-B2 Polyoxyalkylene compound and method for making CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) 2008-10-07 US disclosed