Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300140 | 0.89 | TSHR (0.46) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10214 | 0.89 | EGLN1 (0.50) | TSHRLMNAKDM4EALDH1A1KDM6B | |
| SCHEMBL30150833 | 0.89 | ALDH1A1 (0.53) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11672385 | 0.87 | EGLN1 (0.48) | TSHRLMNAKDM4EALDH1A1KDM6B | |
| SCHEMBL21725259 | 0.85 | — | — | |
| SCHEMBL450087 | 0.85 | — | — | |
| SCHEMBL20384143 | 0.85 | TSHR (0.50) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7054607 | 0.84 | TSHR (0.42) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11672397 | 0.84 | FFAR3 (0.44) | TSHR | |
| Methyl Alcohol SCHEMBL28098312 | 0.83 | ALDH1A1 (0.55) | TSHRLMNAALDH1A1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565447-A | ALMOTRIPTAN MALATE; TREATING HEADACHES, MOVEMENT DISORDERS, DEPRESSION, ANXIETY | LABORATORIOS ALMIRALL S.A. (ES) | 1996-10-15 | — | — | US | disclosed |
| EP-0206375-A1 | Liquid cleaning and softening compositions | UNILEVER N.V. (NL) | 1986-12-30 | — | — | EP | disclosed |
| EP-0203660-A1 | Liquid cleaning and softening compositions | UNILEVER N.V. (NL) | 1986-12-03 | — | — | EP | disclosed |