Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326549 | 0.82 | GBA1 (0.41) | TSHRHPGDGBA1 | |
| SCHEMBL15326653 | 0.82 | GBA1 (0.41) | TSHRHPGDGBA1 | |
| SCHEMBL14000857 | 0.82 | GBA1 (0.41) | TSHRHPGDGBA1 | |
| SCHEMBL14000856 | 0.75 | GBA1 (0.52) | TSHRHPGDGBA1 | |
| SCHEMBL3269289 | 0.73 | GBA1 (0.50) | TSHRHPGDGBA1 | |
| SCHEMBL14027874 | 0.73 | GBA1 (0.34) | TSHRHPGDGBA1 | |
| SCHEMBL15326632 | 0.71 | GBA1 (0.41) | PPARGPPARDPPARATSHRGBA1 | |
| SCHEMBL8499786 | 0.71 | L3MBTL1 (0.47) | TSHRLTA4HTDP1L3MBTL1 | |
| SCHEMBL14627580 | 0.68 | CYP3A4 (0.37) | PPARGPPARDPPARATSHRGBA1 | |
| SCHEMBL7749078 | 0.67 | GBA1 (0.70) | TSHRGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7453006-B2 | Inositol derivatives for increasing chloride secretion and inhibiting inflammation | INOLOGIC, INC. (US) | 2008-11-18 | — | — | US | disclosed |