Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522971 | 0.87 | MEN1 (0.56) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL11559248 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL14028642 | 0.82 | KDM4E (0.55) | ALDH1A1ACHETSHRL3MBTL1 | |
| SCHEMBL1303146 | 0.81 | LTA4H (0.62) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL40675 | 0.80 | KDM4A (0.66) | SMN1; SMN2CARM1PRMT6PRMT8ACHE | |
| SCHEMBL5479984 | 0.78 | CARM1 (0.56) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL4802333 | 0.78 | NPC1 (0.51) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL21908927 | 0.78 | LTA4H (0.62) | SMN1; SMN2KDM4AKDM4CSIGMAR1L3MBTL1 | |
| SCHEMBL14028641 | 0.77 | KMT2A (0.64) | TSHR | |
| SCHEMBL13359820 | 0.77 | CARM1 (0.59) | SMN1; SMN2CARM1PRMT6PRMT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432239-B2 | Polyoxyalkylene compound and method for making | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 2008-10-07 | — | — | US | disclosed |