SCHEMBL14029125

SCHEMBL14029125

CSCC(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CTSG P08311 2/20 0.50
▸ ALB P02768 1/20 0.50
▸ NPR1 P16066 1/20 0.49
▸ NPR3 P17342 1/20 0.49
▸ BECN1 Q14457 6/20 0.48
▸ BCL2L1 Q07817 2/20 0.47
▸ BAD Q92934 2/20 0.47
▸ F11 P03951 1/20 0.46
▸ TSLP Q969D9 2/20 0.46
▸ PLAU P00749 2/20 0.46
▸ TNFSF11 O14788 1/20 0.45
▸ CSNK2A2 P19784 1/20 0.45
▸ CSNK2B P67870 1/20 0.45
▸ CSNK2A1 P68400 1/20 0.45
▸ CSNK2A3 Q8NEV1 1/20 0.45
▸ MC4R P32245 1/20 0.45
▸ MC3R P41968 1/20 0.45
▸ MC1R Q01726 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13590621 0.94 ALB (0.48) CTSGALBNPR1NPR3BECN1
SCHEMBL9909406 0.93 ALB (0.47) CTSGALBNPR1NPR3BECN1
SCHEMBL13267689 0.92 NPR1 (0.48) CTSGALBNPR1NPR3BECN1
SCHEMBL10327614 0.92 NPR1 (0.48) CTSGALBNPR1NPR3BECN1
SCHEMBL16418037 0.92 NPR1 (0.48) CTSGALBNPR1NPR3BECN1
SCHEMBL13487337 0.91 NPR1 (0.47) CTSGALBNPR1NPR3BECN1
SCHEMBL13486079 0.88 NPR1 (0.51) CTSGALBNPR1NPR3BECN1
SCHEMBL16298642 0.87 ALB (0.47) CTSGALBNPR1NPR3BECN1
SCHEMBL10327411 0.86 NPR1 (0.50) CTSGALBNPR1NPR3BECN1
SCHEMBL12307278 0.85 NPR1 (0.48) ALBNPR1NPR3BECN1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274052-A1 RADIOFLORINATION METHODS GE HEALTHCARE LIMITED (GB) 2008-11-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274052-A1 RADIOFLORINATION METHODS VIP, QRFPR, SSTR4 CTSG 468/4885ALB 2684/4885NPR1 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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