SCHEMBL13487337

SCHEMBL13487337

CSCC(=O)N[C@@H](CCCCNC(C)(C)C)C(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPR1 P16066 1/20 0.47
▸ NPR3 P17342 1/20 0.47
▸ ALB P02768 1/20 0.47
▸ F11 P03951 1/20 0.46
▸ CTSG P08311 2/20 0.46
▸ TSLP Q969D9 3/20 0.45
▸ BCL2L1 Q07817 2/20 0.45
▸ BAD Q92934 2/20 0.45
▸ PLAU P00749 2/20 0.44
▸ BECN1 Q14457 3/20 0.44
▸ CSNK2A2 P19784 1/20 0.43
▸ CSNK2B P67870 1/20 0.43
▸ CSNK2A1 P68400 1/20 0.43
▸ CSNK2A3 Q8NEV1 1/20 0.43
▸ TNFSF11 O14788 1/20 0.43
▸ MC4R P32245 1/20 0.43
▸ MC3R P41968 1/20 0.43
▸ MC1R Q01726 1/20 0.43
▸ KLK7 P49862 1/20 0.43
▸ KLKB1 P03952 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909406 0.95 ALB (0.47) NPR1NPR3ALBF11CTSG
SCHEMBL10327614 0.95 NPR1 (0.48) NPR1NPR3ALBF11CTSG
SCHEMBL14029125 0.91 CTSG (0.50) NPR1NPR3ALBF11CTSG
SCHEMBL16418037 0.90 NPR1 (0.48) NPR1NPR3ALBF11CTSG
SCHEMBL13590621 0.90 ALB (0.48) NPR1NPR3ALBF11CTSG
SCHEMBL10327411 0.89 NPR1 (0.50) NPR1NPR3ALBF11CTSG
SCHEMBL13267689 0.89 NPR1 (0.48) NPR1NPR3ALBF11CTSG
SCHEMBL13486079 0.85 NPR1 (0.51) NPR1NPR3ALBF11CTSG
SCHEMBL16298642 0.83 ALB (0.47) NPR1NPR3ALBF11CTSG
SCHEMBL12307278 0.80 NPR1 (0.48) NPR1NPR3ALBF11TSLP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100034740-A1 RADIOFLUORINATION METHODS GE HEALTHCARE AS (NO) 2010-02-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100034740-A1 RADIOFLUORINATION METHODS CYP2F1, CYP4F2, CYP4F3 NPR1 2747/4885NPR3 1654/4885ALB 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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